Get Your Layers Organized!:
Get into the habit of naming your Layers and grouping them into Folders. It is so much easier to cope with editing your work this way! The second screenshot makes me want to close the file immediately and not edit it ever!
Andrei’s power tip:
To quickly create a group, select the layers you want to group while holding down the Shift key, then press Ctrl+G, or Com+G to group them! And if you want to really geek out on this, you can right-click on a group and color code it 🙂